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Invitrogen
GLRA2 Polyclonal Antibody
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产品信息
PA5-21673
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Extracellular domain of human Glycine Receptor alpha 2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, HepG2, mouse brain.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (95%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glycine receptor; glycine receptor alpha 2 subunit; Glycine receptor subunit alpha-2; glycine receptor, alpha 2; glycine receptor, alpha-2 polypeptide
基因别名: GLR; GLRA2
UniProt ID: (Human) P23416, (Mouse) Q7TNC8
Entrez Gene ID: (Human) 2742, (Mouse) 237213
neuropeptide signaling pathway
synapse assembly
spinal cord development
ion transmembrane transport
synaptic transmission, glycinergic
cellular response to amino acid stimulus
cellular response to zinc ion
cellular response to ethanol
chloride transmembrane transport
transport
ion transport
chloride transport
