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Invitrogen
GM-CSF Polyclonal Antibody, Biotin
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产品信息
PA1-84988
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein GM-CSF.
偶联物
形式
Lyophilized
浓度
0.1 mg/mL
规格
50 µg
保存条件
4°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute with 0.5 mL PBS containing 0.1% BSA. For long term storage the addition of 0.09% sodium azide is recommended. PA1-84988 has a IgG concentration of ~0.1 mg/mL after reconstitution. Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.
This antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA with PA1-84972 as the capture antibody.
靶标信息
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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