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Invitrogen
GNMT Polyclonal Antibody
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GNMT Antibody (PA5-117061) in WB
Western blot analysis of GNMT in extracts of various cell lines. Samples were incubated with GNMT Polyclonal antibody (Product # PA5-117061) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-117061
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human GNMT (NP_0618331)
偶联物
形式
Liquid
浓度
0.9 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse liver, Mouse kidney, Mouse pancreas, Rat liver, Rat kidney
Immunogen sequence: MVDSVYRTRS LGVAAEGLPD QYADGEAARV WQLYIGDTRS RTAEYKAWLL GLLRQHGCQR VLDVACGTGV DSIMLVEEGF SVTSVDASDK MLKYALKERW NRRHEPAFDK WVIEEANWMT LDKDVPQSAE GGFDAVICLG NSFAHLPDCK GDQSEHRLAL KNIASMVRAG GLLVIDHRNY DHILSTGCAP PGKNIYYKSD LTKDVTTSVL IVNNKAHMVT LDYTVQVPGA GQDGSPGLSK FRLSYYPHCL ASFTELLQAA FGGKCQHSVL GDFKPYKPGQ TYIPCYFIHV LKRTD
靶标信息
The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2.1.1.20; Folate-binding protein; glycine methyltransferase; glycine N methyl transferase; Glycine N-methyltransferase
基因别名: Fbp-cII; Gnmt
UniProt ID: (Mouse) Q9QXF8, (Rat) P13255
Entrez Gene ID: (Mouse) 14711, (Rat) 25134
glycogen metabolic process
regulation of gluconeogenesis
methionine metabolic process
one-carbon metabolic process
methylation
S-adenosylmethionine metabolic process
protein homotetramerization
glycine metabolic process
S-adenosylhomocysteine metabolic process
folic acid metabolic process
protein tetramerization
sarcosine metabolic process
