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Invitrogen
GNS Polyclonal Antibody
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GNS Antibody (PA5-95512) in WB
Western blot analysis of GNS in Lane 1: rat lung tissue lysates, Lane 2: rat kidney tissue lysates, Lane 3: rat testis tissue lysates, Lane 4: rat PC-12 whole cell lysates, Lane 5: mouse lung tissue lysates, Lane 6: mouse kidney tissue lysates, Lane 7: mouse testis tissue lysates, Lane 8: mouse spleen tissue lysates, Lane 9: mouse thymus tissue lysates. Electrophoresis was performed with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V Resolving gel, Time: 2-3 hours), transferred to a nitrocellulose membrane and blocked using 5% Non-fat Milk/TBS... View More
产品信息
PA5-95512
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human GNS recombinant protein (Position: W238-R355).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human PANC-1 whole cell, human SGC-7901 whole cell, rat lung tissue, rat kidney tissue, rat testis tissue, rat PC-12 whole cell, mouse lung tissue, mouse kidney tissue, mouse testis tissue, mouse spleen tissue, mouse thymus tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G6S; glucosamine -6-sulfatase; Glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase
基因别名: 2610016K11Rik; AU042285; C87209; G6S; GNS; N28088
UniProt ID: (Human) P15586, (Mouse) Q8BFR4
Entrez Gene ID: (Human) 2799, (Mouse) 75612, (Rat) 299825
