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Proteintech
GOPC Polyclonal Antibody
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产品信息
12163-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GOPC Fusion Protein Ag2804 (1-370 aa encoded by BC009553)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSAGGPCPA AAGGGPGGAS CSVGAPGGVS MFRWLEVLEK EFDKAFVDVD LLLGEIDPDQ ADITYEGRQK MTSLSSCFAQ LCHKAQSVSQ INHKLEAQLV DLKSELTETQ AEKVVLEKEV HDQLLQLHSI QLQLHAKTGQ SADSGTIKAK LERELEANKK EKMKEAQLEA EVKLLRKENE ALRRHIAVLQ AEVYGARLAA KYLDKELAGR VQQIQLLGRD MKGPAHDKLW NQLEAEIHLH RHKTVIRACR GRNDLKRPMQ APPGHDQDSL KKSQGVGPIR KVLLLKEDHE GLGISITGGK EHGVPILISE IHPGQPADRC GGLHVGDAIL AVNGVNLRDT KHKEAVTILS QQRGEIEFEV VYVAPEVDSD D (1-370 aa encoded by BC009553)
靶标信息
PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CFTR-associated ligand; dJ94G16.2 PIST; Fused in glioblastoma; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST
基因别名: 2210402P09Rik; AI844555; CAL; dJ94G16.2; FIG; GOPC; GOPC1; PIST
UniProt ID: (Human) Q9HD26, (Mouse) Q8BH60
Entrez Gene ID: (Human) 57120, (Mouse) 94221, (Rat) 309774
