FIGURE: 1 / 4
Peptide sequence: LGSLFLWREL QEAPLSLAEG WQLFLAALAQ GVLEHHTYGA LLFPLLSLGL
Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 100%
Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.
Protein Aliases: anchor attachment protein 1 (Gaa1p, yeast) homolog; GAA1 protein homolog; glycophosphatidylinositol anchor attachment 1; Glycosylphosphatidylinositol anchor attachment 1 protein; glycosylphosphatidylinositol anchor attachment protein 1 homolog; GPAA1P anchor attachment protein 1 homolog; GPI anchor attachment protein 1; GPI transamidase subunit; hGAA1
Gene Aliases: GAA1; GPAA1; hGAA1
UniProt ID: (Human) O43292
Entrez Gene ID: (Human) 8733