The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.
蛋白别名: activation/proliferation-associated protein 1; caprin 1; Caprin-1; Cell cycle-associated protein 1; cytop; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; Membrane component chromosome 11 surface marker 1; membrane component, chromosome 11, surface marker 1; p137GPI; RNA granule protein 105
基因别名: AL022980; Caprin-1; CAPRIN1; G5E5; GPI p137; Gpiap; GPIAP1; GPIP137; GRIP137; M11S1; Mmgpip137; P137; p137GPI; RNG105
分子生物学功能: RNA metabolism protein