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Invitrogen
GPR1 Polyclonal Antibody
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GPR1 Antibody (PA1-145) in IHC (P)
Immunohistochemistry analysis of GPR1 was performed on human kidney duct tissue. To expose target proteins, antigen retrieval was performed by microwaving tissues for 20 minutes in 10mM sodium citrate buffer (pH 6.0). Tissue slides were probed with a GPR1 polyclonal antibody (Product # PA1-145) at a dilution of 1:1000, overnight at 4C in a humidified chamber without (left panel) or with peptide blocking con... View More
产品信息
PA1-145
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated Cys-SGTVSEQLRNSETKNL-Abu-LLETAQ
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
IHC(P) analysis shows positive staining of GPR1 in human kidney duct tissue.
靶标信息
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR1 is an orphan receptor for the inflammation-associated leukocyte chemoattractant chemerin, suggesting a role for this receptor in the regulation of inflammation. In yeast, G protein-coupled receptor 1 senses glucose and controls filamentous growth. It acts upstream of adenylate cyclase and is required for glucose activation of cAMP synthesis in concert with a glucose phosphorylation-dependent mechanism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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