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Alomone Labs, LTD
GPR12 (extracellular) Polyclonal Antibody
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GPR12 (extracellular) Antibody (AGR-062-200UL) in IHC (F)
Expression of GPR12 in rat cortex. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-GPR12 (extracellular) Antibody (#AGR-062), (1:300), followed by donkey Anti-rabbit-biotin and Streptavidin-Cy3. A. Staining in the parietal cortex region, showed GPR12 immunoreactivity (red) in glial cell outlines (arrows). B. Pre-incubation of the Antibody with GPR12 (extracellular) Bloc... View More
产品信息
AGR-062-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)EDPKVNLSGLPRD, corresponding to amino acid residues 3-15 of mouse GPR12, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ18149; FLJ97704; G-protein coupled receptor 12; GPCR01; MGC138349; MGC138351; R334
基因别名: Gpcr01; Gpcr12; Gpcr20; Gpcr21; Gpr12
UniProt ID: (Mouse) P35412, (Rat) P30951
Entrez Gene ID: (Mouse) 14738, (Rat) 80840
