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Invitrogen
GPR177 Polyclonal Antibody
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GPR177 Antibody (PA5-110582) in WB
Western blot analysis of GPR177 in extracts of various cell lines. Samples were incubated with GPR177 Polyclonal antibody (Product # PA5-110582) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110582
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 43-232 of human WLS (NP_0010022923)
偶联物
形式
Liquid
浓度
1.17 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: YMSVKCVDAR KNHHKTKWFV PWGPNHCDKI RDIEEAIPRE IEANDIVFSV HIPLPHMEMS PWFQFMLFIL QLDIAFKLNN QIRENAEVSM DVSLAYRDDA FAEWTEMAHE RVPRKLKCTF TSPKTPEHEG RYYECDVLPF MEIGSVAHKF YLLNIRLPVN EKKKINVGIG EIKDIRLVGI HQNGGFTKVW
靶标信息
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: evenness interrupted homolog; EVI; G protein-coupled receptor 177; Integral membrane protein GPR177; Protein evenness interrupted homolog; Protein wntless homolog; Putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373
基因别名: 5031439A09Rik; AI173978; AI987742; C1orf139; EVI; GPR177; mig-14; MRP; UNQ85/PRO18667; WLS
UniProt ID: (Human) Q5T9L3, (Mouse) Q6DID7, (Rat) Q6P689
Entrez Gene ID: (Human) 79971, (Mouse) 68151, (Rat) 362065
mesoderm formation
multicellular organism development
anterior/posterior axis specification
Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
biological_process
intracellular protein transport
positive regulation of Wnt signaling pathway
midbrain development
hindbrain development
exocrine pancreas development
positive regulation of I-kappaB kinase/NF-kappaB signaling
Wnt protein secretion
positive regulation of Wnt protein secretion
