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Invitrogen
GPR56 Polyclonal Antibody
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图: 1 / 4
GPR56 Antibody (720373) in ICC/IF
HEK 293 cells were grown on poly-L-lysine-coated coverslips overnight. Cells were then transiently transfected with GPR56. After 24 h, cells were fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with Anti-GPR56 Rabbit Polyclonal Antibody (Product # 720373 at a concentration of 2 µg/mL). Cells were then incubated with Alexa488-conjugated secondary antibody for 2... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
720373
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to Human ADGRG1 (aa 252-265)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2-7.4, with 0.1% BSA, 30% glycerol
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Cat and Bovine.
靶标信息
GPR56 is a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 7-transmembrane protein with no EGF-like N-terminal domains-1; Cyt28; DKFZp781L1398; G protein-coupled receptor 56; SLR32; testicular tissue protein Li 77; unnamed protein product
基因别名: BFPP; BPPR; CDCBM14B; CDCBM15A; GPR56; TM7LN4; TM7XN1
UniProt ID: (Human) Q9Y653
Entrez Gene ID: (Human) 9289
angiogenesis
cell adhesion
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
Rho protein signal transduction
cell-cell signaling
brain development
negative regulation of cell proliferation
positive regulation of signal transduction
cell migration
cerebral cortex radial glia guided migration
layer formation in cerebral cortex
positive regulation of Rho protein signal transduction
tube development
regulation of cell proliferation
positive regulation of cell adhesion
anatomical structure formation involved in morphogenesis
seminiferous tubule development
regulation of platelet aggregation
synapse pruning
negative regulation of ferroptosis
Rho-activating G protein-coupled receptor signaling pathway
positive regulation of vascular endothelial growth factor signaling pathway
negative regulation of neuron migration
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
