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IHC(P) analysis shows positive staining of GPR61 in human pancreatic islets and enteric ganglion.
WB analysis shows GPR61 in glyco-protein enriched fractions from mock transfected or GPR61 overexpressed 293 cells. The GPR61 antiserum showed specific detection of GPR61 over other tested GPRs.
GPR61 exists in different glycosylated forms and can form dimers and oligomers. Consequently it appears as a long smear on WB or is detected at multiple molecular weights.
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR61 is a member of this family (subfamily Orphan-A). It has been reported to be expressed in several regions of brain, including caudate, putamen, and thalamus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Biogenic amine receptor-like G-protein coupled receptor; biogenic amine receptor-like GPCR; G-protein coupled receptor 61
基因别名: BALGR; GPCR3; GPR61
UniProt ID: (Human) Q9BZJ8
Entrez Gene ID: (Human) 83873