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PA1-41625 detects G-Protein-Coupled Receptor 83 in canine, human, monkey, chimpanzee, mouse and rat samples.
This antibody is predicted to react with bovine, chicken and opossum based on sequence homology.
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。