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Proteintech
GRAF Polyclonal Antibody
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产品信息
17747-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GRAF Fusion Protein Ag12008 (403-759 aa encoded by BC068555)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RGINEQGLY RIVGVNSRVQ KLLSVLMDPK TASETETDIC AEWEIKTITS ALKTYLRMLP GPLMMYQFQR SFIKAAKLEN QESRVSEIHS LVHRLPEKNR QMLQLLMNHL ANVANNHKQN LMTVANLGVV FGPTLLRPQE ETVAAIMDIK FQNIVIEILI ENHEKIFNTV PDMPLTNAQL HLSRKKSSDS KPPSCSERPL TLFHTVQSTE KQEQRNSIIN SSLESVSSNP NSILNSSSSL QPNMNSSDPD LAVVKPTRPN SLPPNPSPTS PLSPSWPMFS APSSPMPTSS TSSDSSPVST PFRKAKALYA CKAEHDSELS FTAGTVFDNV HPSQEPGWLE GTLNGKTGLI PENYVEFL (403-759 aa encoded by BC068555)
靶标信息
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ42530; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); Oligophrenin-1-like protein; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
基因别名: 1810044B20Rik; 2610010G17Rik; 4933432P15Rik; AI853435; ARHGAP26; GRAF; GRAF1; KIAA0621; mKIAA0621; OPHN1L; OPHN1L1
UniProt ID: (Human) Q9UNA1, (Mouse) Q6ZQ82
Entrez Gene ID: (Human) 23092, (Mouse) 71302
