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Proteintech
GRAF Recombinant Rabbit Monoclonal Antibody (240086A11)
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产品信息
83206-1-RR
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
240086A11
抗原
GRAF fusion protein Ag12008
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: RGINEQGLYR IVGVNSRVQK LLSVLMDPKT ASETETDICA EWEIKTITSA LKTYLRMLPG PLMMYQFQRS FIKAAKLENQ ESRVSEIHSL VHRLPEKNRQ MLQLLMNHLA NVANNHKQNL MTVANLGVVF GPTLLRPQEE TVAAIMDIKF QNIVIEILIE NHEKIFNTVP DMPLTNAQLH LSRKKSSDSK PPSCSERPLT LFHTVQSTEK QEQRNSIINS SLESVSSNPN SILNSSSSLQ PNMNSSDPDL AVVKPTRPNS LPPNPSPTSP LSPSWPMFSA PSSPMPTSST SSDSSPVSTP FRKAKALYAC KAEHDSELSF TAGTVFDNVH PSQEPGWLEG TLNGKTGLIP ENYVEFL
靶标信息
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ42530; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); Oligophrenin-1-like protein; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
基因别名: ARHGAP26; GRAF; GRAF1; KIAA0621; OPHN1L; OPHN1L1
UniProt ID: (Human) Q9UNA1
Entrez Gene ID: (Human) 23092
