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Invitrogen
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Immunogen sequence: RDSVYDLLRR VCTHLQPSSK KSLSVREFSG EPESLEVLIP EMKWRKVCPS SRSLSLPDNI PCIPPSSVDS TDSFFPSRKP PMSEKSRAQV ASENGGRWAW PMPGWGPACP KKMPNCSPTA KNAVYE
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 47%.
Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner. Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE).
仅用于科研。不用于诊断过程。未经明确授权不得转售。