This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
蛋白别名: Adapter protein GRID; GRB-2-like protein; GRB2-related adapter protein 2; GRB2-related protein with insert domain; GRB2L; GRBLG; GRBX; Grf-40; Grf40 adapter protein; Growth factor receptor-binding protein; growth factor receptor-bound protein 2-related adaptor protein 2; Hematopoietic cell-associated adapter protein GrpL; hematopoietic cell-associated adaptor protein GRPL; P38; Protein GADS; RP3-370M22.1; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule
基因别名: GADS; GRAP-2; GRAP2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38
UniProt ID: (Human) O75791
Entrez Gene ID: (Human) 9402