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Invitrogen
GRASP1 Polyclonal Antibody
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产品信息
PA1-4662
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C-terminal region of rat GRIPAP1 conjugated to KLH
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, canine, human and mouse based on 100% sequence homology.
This antibody is specific for the ~95 kDa GRASP protein.
靶标信息
PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GRASP-1; GRIP-1; GRIP-associated protein 1; GRIP1; GRIP1-associated protein 1; HCMV-interacting protein; MPMGp800B12492Q3
基因别名: AI854681; DXImx47e; GRASP-1; Grasp1; Gripap1; Kiaa1167; mKIAA1167; Sfc10
UniProt ID: (Rat) Q9JHZ4, (Mouse) Q8VD04
Entrez Gene ID: (Rat) 116493, (Mouse) 54645
