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Invitrogen
GRB10 Polyclonal Antibody
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GRB10 Antibody (PA5-79322) in IHC
Genes 2021 -
Figure 2 Expression of "embryo-high" imprinted genes in the developing and postnatal pituitary gland . In situ hybridisation (ISH) using antisense riboprobes against insulin growth factor 2 ( Igf2 ) ( A - G ), cyclin-dependent kinase inhibitor 1C ( Cdkn1c ) ( H - N ), neuronatin ( Nnat ) ( O - U ) and immunohistochemistry (IHC) against growth-factor receptor bound protein 10 (GRB10) ( V-Ac ) and sex-determi... View More
产品信息
PA5-79322
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human GRB10.
偶联物
形式
Lyophilized
浓度
500 µg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
The synthetic peptide sequence is 550-567aa, DGQTFFSLDDGNTKFSD
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
靶标信息
GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
