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Proteintech
GRIA4 Polyclonal Antibody
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产品信息
23350-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GRIA4 Fusion Protein Ag19949 (87-229 aa encoded by BC167786)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: YSRGVFAIF GLYDKRSVHT LTSFCSALHI SLITPSFPTE GESQFVLQLR PSLRGALLSL LDHYEWNCFV FLYDTDRGYS ILQAIMEKAG QNGWHVSAIC VENFNDVSYR QLLEELDRRQ EKKFVIDCEI ERLQNILEQI VSVG (87-229 aa encoded by BC167786)
靶标信息
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AMPA-selective glutamate receptor 4; GluA4; GluR-4; GluR-D; glutamate receptor; Glutamate receptor 4; glutamate receptor channel alpha 4; Glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); spike wave 1
基因别名: GluA4; Glur-4; GluR-D; GLUR4; GLUR4C; Gluralpha4; GLURD; GRIA4; spkw1
UniProt ID: (Human) P48058, (Mouse) Q9Z2W8, (Rat) P19493
Entrez Gene ID: (Human) 2893, (Mouse) 14802, (Rat) 29629
transport
glutamate receptor signaling pathway
chemical synaptic transmission
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
response to fungicide
ion transport
synaptic transmission, glutamatergic
modulation of synaptic transmission
positive regulation of synaptic transmission, glutamatergic
regulation of synapse structure or activity
