Alomone Labs, LTD

GRIK3 (GluK3) (extracellular) Polyclonal Antibody

Name: GRIK3 (GluK3) (extracellular) Polyclonal Antibody
Brand: Alomone Labs, LTD
SKU: AGC-040-200UL
Availability: InStock

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说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (2)

GRIK3 (GluK3) (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

图: 1 / 2

GRIK3 (GluK3) (extracellular) Antibody (AGC-040-200UL) in IHC (F)

Expression of GluR7 in mouse hippocampus and rat cerebellum - Immunohistochemical staining of immersion-fixed, free floating frozen brain sections using Anti-GRIK3 (GluK3) (extracellular) Antibody (#AGC-040), (1:400).A. GluR7 staining (red) in mouse hippocampus reveals expression in the pyramidal (P) layer (arrow).B. GluR7 staining (red) in rat cerebellum reveals expression in the Purkinje (P) layer (horizo... View More

GRIK3 (GluK3) (extracellular) Antibody in Western Blot (WB)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

Immunogen image

Immunogen Image GRIK3 (GluK3) (extracellular) Polyclonal Antibody

产品信息

AGC-040-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（冰冻） (IHC (F))

1:400

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)DGPNAQVMNAEEH, corresponding to amino acid residues 46-58 of rat kainate receptor GluK3, Extracellular, N-terminus

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

160 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: EAA5; Excitatory amino acid receptor 5; GluK3; GluR-7; glutamate receptor; Glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor subunit kainate subtype

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基因别名: 9630027E11; GluK3; Glur-7; GLUR7; GluR7-3; GRIK3

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UniProt ID: (Rat) P42264, (Mouse) B1AS29

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Entrez Gene ID: (Rat) 298521, (Mouse) 14807

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功能

adenylate cyclase inhibiting G-protein coupled glutamate receptor activity ionotropic glutamate receptor activity extracellular-glutamate-gated ion channel activity glutamate receptor activity kainate selective glutamate receptor activity receptor activity ion channel activity protein binding transmembrane signal receptor

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