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The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signaling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: glucagon; glucagon-like peptide-1; Pro-glucagon
基因别名: Gcg; GLP-1; Glu; PPG
UniProt ID: (Mouse) P55095
Entrez Gene ID: (Mouse) 14526, (Rat) 24952