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Proteintech
GSTA2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
10505-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GSTA2 Fusion Protein Ag0781 (1-222 aa encoded by BC002895)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
60 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAEKPKLHY SNIRGRMESI RWLLAAAGVE FEEKFIKSAE DLDKLRNDGY LMFQQVPMVE IDGMKLVQTR AILNYIASKY NLYGKDIKEK ALIDMYIEGI ADLGEMILLL PFTQPEEQDA KLALIQEKTK NRYFPAFEKV LKSHGQDYLV GNKLSRADIH LVELLYYVEE LDSSLISSFP LLKALKTRIS NLPTVKKFLQ PGSPRKPPMD EKSLEESRKI FRF (1-222 aa encoded by BC002895)
靶标信息
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 13-hydroperoxyoctadecadienoate peroxidase; Androst-5-ene-3,17-dione isomerase; Glutathione S-transferase A2; Glutathione S-transferase alpha-1; Glutathione S-transferase GT41A; glutathione S-transferase Ya subunit; Glutathione S-transferase Ya-1; Glutathione-S-transferase alpha type (Yc?); glutathione-S-transferase, alpha type2; GST 1-1; GST 1a-1a; GST A1-1; GST B; GST class-alpha member 2; GST HA subunit 2; GST Ya1; GST-gamma; GSTA2-2; GTH2; Ligandin
基因别名: GST2; Gst2-2; Gsta1; GSTA2; Gstc-2; Gstc2
UniProt ID: (Rat) P00502, (Mouse) P10648
Entrez Gene ID: (Rat) 24422, (Mouse) 14858
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
