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Invitrogen
GSTA3/GSTA5 Polyclonal Antibody
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产品信息
PA5-142682
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-EMDPGIVDNFPLLK.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Additional Information: This antibody is expected to cross-react to the homologous Mouse protein Gsta3.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
靶标信息
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GHS transferase; Glutathione S-transferase A3; Glutathione S-transferase alpha-2; Glutathione S-transferase alpha-5; glutathione S-transferase Ya subunit; Glutathione S-transferase Ya-2; Glutathione S-transferase Ya3; Glutathione S-transferase Yc; Glutathione S-transferase Yc-2; glutathione S-transferase Yc2 subunit; glutathione transferase YA subunit; GST 1b-1b; GST A2-2; GST A5-5; GST class-alpha member 3; GST Ya2; GST Yc2; uncharacterized protein LOC100042314
基因别名: ENSMUSG00000074179; Gst2-3; Gsta2; Gsta3; Gsta5; Gstyc; Gstyc2; Yc2
UniProt ID: (Mouse) P30115, (Rat) P46418, (Rat) P04903
Entrez Gene ID: (Mouse) 100042314, (Mouse) 14859, (Rat) 494500, (Rat) 494499
