Proteintech

Galectin 9 Polyclonal Antibody

15 篇参考文献
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说明书
实验方案
问题与答案
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说明书
实验方案
问题与答案
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说明书
实验方案
问题与答案
技术支持
Galectin 9 Polyclonal Antibody

产品信息

17938-1-AP

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
查看8篇已发表文章 8篇已发表文章

免疫组化 (IHC)

Assay-dependent
查看4篇已发表文章 4篇已发表文章

免疫细胞化学 (ICC/IF)

1:50-1:500
-

免疫沉淀 (IP)

0.5-4.0 µg
查看1篇已发表文章 1篇已发表文章

其他PubMed (Misc)

-
查看1篇已发表文章 1篇已发表文章

不适用 (N/A)

-
查看1篇已发表文章 1篇已发表文章
产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Galectin 9 Fusion Protein Ag12209 (1-323 aa encoded by BC110340)
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.17 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MAFSGSQAP YLSPAVPFSG TIQGGLQDGL QITVNGTVLS SSGTRFAVNF QTGFSGNDIA FHFNPRFEDG GYVVCNTRQN GSWGPEERKT HMPFQKGMPF DLCFLVQSSD FKVMVNGILF VQYFHRVPFH RVDTISVNGS VQLSYISFQP PGVWPANPAP ITQTVIHTVQ SAPGQMFSTP AIPPMMYPHP AYPMPFITTI LGGLYPSKSI LLSGTVLPSA QRFHINLCSG NHIAFHLNPR FDENAVVRNT QIDNSWGSEE RSLPRKMPFV RGQSFSVWIL CEAHCLKVAV DGQHLFEYYH RLRNLPTINR LEVGGDIQLT HVQT (1-323 aa encoded by BC110340)

靶标信息

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; lectin, galactose binding, soluble 5; lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; urate transporter/channel protein

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基因别名: AA407335; AI194909; AI265545; gal-9; galectin-9; HUAT; LGALS35; Lgals5; LGALS9; LGALS9A

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UniProt ID: (Human) O00182, (Mouse) O08573

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Entrez Gene ID: (Human) 3965, (Mouse) 16859

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功能
signal transducer activity galactose binding enzyme binding carbohydrate binding disaccharide binding galactoside binding extracellular matrix protein
参与通路
natural killer cell tolerance induction chemotaxis inflammatory response female pregnancy positive regulation of gene expression negative regulation of gene expression response to lipopolysaccharide regulation of interleukin-4 production regulation of interleukin-5 production negative regulation of chemokine production negative regulation of interferon-gamma production negative regulation of tumor necrosis factor production positive regulation of interleukin-4 production positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response toll-like receptor 2 signaling pathway toll-like receptor 4 signaling pathway p38MAPK cascade positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of mast cell degranulation negative regulation of natural killer cell mediated cytotoxicity negative regulation of activated T cell proliferation positive regulation of viral entry into host cell positive regulation of interleukin-1 beta secretion positive regulation of NF-kappaB transcription factor activity maternal process involved in female pregnancy positive regulation of activated T cell autonomous cell death ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade response to interleukin-1 cellular response to interferon-gamma positive regulation of transforming growth factor beta production positive regulation of monocyte chemotactic protein-1 production mature conventional dendritic cell differentiation cellular response to virus regulation of p38MAPK cascade positive regulation of interferon-gamma secretion positive regulation of tumor necrosis factor secretion positive regulation of interleukin-8 secretion positive regulation of dendritic cell chemotaxis negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of interleukin-13 secretion positive regulation of dendritic cell apoptotic process positive regulation of interleukin-6 secretion positive regulation of interleukin-10 secretion positive regulation of interleukin-12 secretion positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell positive regulation of dendritic cell differentiation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
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