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Proteintech
Gamma Catenin Monoclonal Antibody (1A5D10), CoraLite® Plus 488
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产品信息
CL488-66445
产品规格
种属反应
Dog,
Human,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A5D10
抗原
Gamma Catenin fusion protein Ag1627
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: LVNQLSVDD VNVLTCATGT LSNLTCNNSK NKTLVTQNSG VEALIHAILR AGDKDDITEP AVCALRHLTS RHPEAEMAQN SVRLNYGIPA IVKLLNQPNQ WPLVKATIGL IRNLALCPAN HAPLQEAAVI PRLVQLLVKA HQDAQRHVAA GTQQPYTDGV RMEEIVEGCT GALHILARDP MNRMEIFRLN TIPLFVQLLY SSVENIQRVA AGVLCELAQD KEAADAIDAE GASAPLMELL HSRNEGTATY AAAVLFRISE DKNPDYRKRV SVELTNSLFK HDPAAWEAAQ SMIPINEPYG DDLDATYRPM YSSDVPLDPL EMHMDMDGDY PIDTYSDGLR PPYPTADHML A
靶标信息
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735; plakoglobin
基因别名: ARVD12; CTNNG; DP3; DPIII; JUP; PDGB; Pg; PKGB
UniProt ID: (Pig) Q8WNW3, (Human) P14923, (Rat) Q6P0K8
Entrez Gene ID: (Pig) 397592, (Dog) 480522, (Human) 3728, (Rat) 81679
transcription coactivator activity
signal transducer activity
structural molecule activity
structural constituent of cell wall
protein binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
cadherin binding involved in cell-cell adhesion
nuclear hormone receptor binding
desmosome assembly
cytoskeletal anchoring at plasma membrane
signal transduction
single organismal cell-cell adhesion
cell migration
adherens junction organization
adherens junction assembly
regulation of cell proliferation
positive regulation of protein import into nucleus
skin development
detection of mechanical stimulus
positive regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
endothelial cell-cell adhesion
cellular response to indole-3-methanol
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
positive regulation of canonical Wnt signaling pathway
regulation of ventricular cardiac muscle cell action potential
cell adhesion
regulation of cell fate specification
positive regulation of transcription from RNA polymerase II promoter
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
