Glutamate dehydrogenase 2, Glud2, is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. Diseases associated with GLUD2 include Parkinson Disease, Late-Onset and Hyperinsulinemic Hypoglycemia, Familial, 6. Among its related pathways are GABA shunt and Carbon metabolism.
蛋白别名: GDH 2; GluR delta2; Glutamate dehydrogenase 2, mitochondrial; glutamate dehydrogenase pseudogene 1; testicular secretory protein Li 14
基因别名: GDH2; GLUD2; GLUDP1
UniProt ID: (Human) P49448
Entrez Gene ID: (Human) 2747