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Invitrogen
GluR3 (extracellular) Polyclonal Antibody
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GluR3 (extracellular) Antibody (PA5-111782) in IHC (F)
Immunohistochemistry analysis of GluR3 in frozen mouse cerebellum tissue sections using GluR3 (extracellular) Antibody (Product # PA5-111782). A) Distribution of GRIA3 (red). B) Distribution of glial fibrillary acidic protein (green). C) Merge of the two images indicates that GRIA3 is localized to Bergmann glia (vertical arrow) and to Purkinje cell soma (horizontal arrow). DAPI is used as the counterstain (... View More
产品信息
PA5-111782
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 60-73 of rat GluR3 (Extracellular, N-terminus)
偶联物
形式
Lyophilized
浓度
0.6 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)EKPFHLN YHVDHLD
Homology: Mouse, human, dog amino acid residues are identical.
靶标信息
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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