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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:200-1:500 | - |
免疫组化 (IHC) |
1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Peptide (C)KTRYSQKIGDDLS, corresponding to amino acid residues 200-212 of rat Glucagon Receptor |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
0.8 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 1% BSA |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2735850 |
Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.
Reconstitute using 50 uL deionized water.
Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GL-R; Glucagon receptor; glucagon receptor perhaps same as Niddm3
基因别名: GCGR; GGR; GL-R; GR
UniProt ID: (Human) P47871, (Mouse) Q61606, (Rat) P30082
Entrez Gene ID: (Human) 2642, (Mouse) 14527, (Rat) 24953
分子生物学功能:
transmembrane signal receptor
