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Invitrogen
Glutaminase Recombinant Rabbit Monoclonal Antibody (6H5L15)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 5
Glutaminase Antibody (701965) in ICC/IF
Knockdown of GLS was achieved by transfecting Hep G2 cells with GLS specific siRNAs (Silencer® select Product # s5839, s5840). Immunofluorescence analysis was performed using untransfected Hep G2 cells (panels a, d), transfected with non-specific scrambled siRNA (panels b,e) and transfected with GLS specific siRNAs (panel c,f). Cells were fixed, permeabilized, and probed with GLS (6H5L15), Recombinant Rabbi... View More
产品信息
701965
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6H5L15
抗原
Protein corresponding to Human GLS (aa 251-533)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2633041
产品详细信息
This antibody is predicted to react with Monkey, Rabbit, Rat and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Glutaminase is a phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. It is primarily expressed in the brain and kidney and plays an essential role in generating energy for metabolism, synthesizing neurotransmitter glutamate, and maintaing acid-based balance in the kidney. There are alternate splicing results in multiple transcript variants in the Glutaminase gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DKFZp686O15119; FLJ10358; GLS; glutaminase C; Glutaminase kidney isoform, mitochondrial; glutaminase, phosphate-activated; K-glutaminase; L-glutamine amidohydrolase
基因别名: 6330442B14; AAD20; AI314027; B230365M23Rik; GAC; GAM; GLS; GLS1; Glut; KGA; KIAA0838; RATGLUT
UniProt ID: (Human) O94925, (Mouse) D3Z7P3, (Rat) P13264
Entrez Gene ID: (Human) 2744, (Mouse) 14660, (Rat) 24398
