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Invitrogen
Gossypol Recombinant Mouse Monoclonal Antibody (1H5)
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Gossypol Antibody (MA566469) in SDS-PAGE
SDS-PAGE characterization of Gossypol under reducing conditions. Lane M: Protein marker (kDa); Lane GOS: Purified Gossypol Recombinant Monoclonal (Product # MA566469). Gossypol showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-294.
产品信息
MA566469
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1H5
抗原
Conjugate of GOS hapten and KLH.
偶联物
形式
Liquid
浓度
9.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Gossypol is a polyphenolic compound derived primarily from cotton plants, recognized for its diverse biological activities and potential therapeutic applications. It is characterized by its unique structure, which includes two naphthalene rings connected by a binaphthyl linkage, contributing to its bioactivity. Gossypol exhibits significant antitumor properties, functioning through mechanisms such as apoptosis induction and inhibition of cell proliferation. Its derivatives, including gossypol Schiff bases, apogossypol, and gossypolone, have been synthesized to enhance its pharmacological efficacy. These derivatives retain the bioactivities of gossypol, with modifications aimed at improving solubility and reducing toxicity. The compound's ability to interact with various cellular targets makes it a promising candidate for drug development, particularly in cancer therapy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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