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Invitrogen
Gram Negative Endotoxin Monoclonal Antibody (B40/23)
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产品信息
MA1-83136
产品规格
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
B40/23
抗原
E. coli O:111 B4 J5 cells.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
4°C or -20°C if preferred
运输条件
Wet ice
RRID
产品详细信息
Mouse anti Endotoxin antibody, clone GNE11-270.3.1 recognizes endotoxin from many gram negative bacteria and cross reacts with Klebsiella pneumoniae, Salmonella typhimurium and Shigella sonnei.
靶标信息
Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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