Invitrogen
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
酶联免疫吸附实验 (ELISA) |
1-10 µg/mL | - |
产品规格 | |
---|---|
种属反应 |
Bacteria |
宿主/亚型 |
Mouse / IgM |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
HEC10-172.5 |
抗原 |
E. coli serotypes: O:111, B4 J5. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.06 mg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.4 |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_1074810 |
MA1-10690 detects Endotoxin from K. pneumoniae, S. marcescens, P. mirabilis, P. vulgaris, and Ps. aeruginosa samples.
MA1-10690 has been successfully used in ELISA applications.
The MA1-10690 immunogen is E. coli serotypes: O:111, B4 J5.
Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。