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This product is predicted to work in Western Blot at a dilution of 1:1,000.
Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: H2B histone family, member B; H2B-clustered histone 5; H2B/a; H2B/b; H2B/g; H2B/h; H2B/k; H2B/l; HIRA-interacting protein 2; histone 1, H2bd; Histone H2B mono methyl R79; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-D; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.a; Histone H2B.b; Histone H2B.g; Histone H2B.h; Histone H2B.k; Histone H2B.l; MONO-METHYL-HISTONE H2B (Arg79); MONO-METHYL-HISTONE H2B (R79)
基因别名: dJ221C16.6; H2B.1B; H2B/b; H2BC10; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BFA; H2BFB; H2BFG; H2BFH; H2BFK; H2BFL; HIRIP2; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI
UniProt ID: (Human) P62807
Entrez Gene ID: (Human) 3017