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Invitrogen
H3K18lac Polyclonal Antibody
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H3K18lac Antibody (PA5-116896) in WB
Western blot analysis of Lactyl-Histone H3 (Lys18) in extracts of MCF7 cells. Samples were incubated with Lactyl-Histone H3 (Lys18) Polyclonal antibody (Product # PA5-116896) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. MCF7 cells were treated by Sodium lactate (100mM) for 24h. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit. Exposure time: 5 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116896
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.78 mg/mL
规格
278 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: MCF7
靶标信息
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H3 histone family, member A; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; HIST1H3A; HIST1H3F; histone 1, H2ai; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 1, H3j; histone 2, H3a; histone 2, H3c2; histone 2, H3ca2; histone cluster 1 H2a family member I like 1; histone cluster 1 H3 family member A; histone cluster 1 H3 family member b; histone cluster 1 H3 family member f; histone cluster 1 H3 family member h; histone cluster 1 H3 family member j; histone cluster 1, H2ai-like; histone cluster 1, H2ai-like1; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 1, H3j; histone cluster 2 H3 family member a; histone cluster 2 H3C family member 2; histone cluster 2, H3a; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; histone H3; histone H3.1; histone H3/a; histone H3/i; histone H3/j; histone H3/k; histone H3/l; histone H3/o; unnamed protein product
基因别名: H3 histone; H3-291; H3-53; H3-614; H3.2-221; H3.2-614; H3/A; H3/i; H3/j; H3/k; H3/l; H3/n; H3/o; H3c1; H3c10; H3c11; H3c13; H3c14; H3c15; H3c2; H3c3; H3c4; H3c6; H3c7; H3c8; H3F1K; H3FA; H3FI; H3FJ; H3FK; H3FL; Hist1; Hist1h2ail; Hist1h2ail1; HIST1H3A; HIST1H3B; HIST1H3F; HIST1H3H; HIST1H3J; HIST2H3A; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1
UniProt ID: (Human) P68431, (Human) Q71DI3, (Rat) Q6LED0, (Mouse) P68433, (Mouse) P84228
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