Invitrogen

H3R12me2a Polyclonal Antibody

Name: H3R12me2a Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-120778
Price: 6127.00 CNY
Availability: InStock

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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H3R12me2a Antibody (PA5-120778) in WB

Western blot analysis of H3R12me2a in extracts of various cell lines. Samples were incubated with H3R12me2a Polyclonal antibody (Product # PA5-120778) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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产品信息

PA5-120778

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic asymmetric dimethylated peptide around R2 of human Histone H3 (NP_0035201)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.41 mg/mL

41 µg

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C, Avoid Freeze/Thaw Cycles

Ambient (domestic); Wet ice (international)

AB_2914350

产品详细信息

Positive test controls include: HeLa acid extract, NIH/3T3 acid extract, C6 acid extract, H3 protein. The target is usually found in the following locations: Chromosome, Nucleus.

Immunogen sequence: MART

靶标信息

Histone H3 is a core DNA-binding protein that, together with other histones, forms nucleosomes to organize chromatin in eukaryotic cells. Histones are essential for transcription regulation, DNA repair, replication, and chromosomal stability. The N-terminal tail of histone H3 extends from the nucleosome core and undergoes various post-translational modifications that influence chromatin structure and function.
H3R12me2a refers to the asymmetric dimethylation of arginine 12 on histone H3, catalyzed by type I protein arginine methyltransferases (PRMTs). This modification occurs on the N-terminal tail and is associated with regulation of chromatin dynamics and gene expression, potentially through modulation of protein-DNA and protein-protein interactions.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: assymetric dimethyl histone; dimethyl histone; H3 histone family, member A; H3 histone family, member B; H3 histone family, member C; H3 histone family, member D; H3 histone family, member F; H3 histone family, member H; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; HIST1H3A; HIST1H3E; HIST1H3F; histone 1, H2ai; histone 1, H3a; histone 1, H3b; histone 1, H3c; histone 1, H3d; histone 1, H3e; histone 1, H3f; histone 1, H3g; histone 1, H3h; histone 1, H3i; histone 1, H3j; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; histone 2, H3d; histone cluster 1 H2a family member I like 1; histone cluster 1 H3 family member A; histone cluster 1 H3 family member b; histone cluster 1 H3 family member c; histone cluster 1 H3 family member d; histone cluster 1 H3 family member e; histone cluster 1 H3 family member f; histone cluster 1 H3 family member g; histone cluster 1 H3 family member h; histone cluster 1 H3 family member i; histone cluster 1 H3 family member j; histone cluster 1, H2ai-like; histone cluster 1, H2ai-like1; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3c; histone cluster 1, H3d; histone cluster 1, H3e; histone cluster 1, H3f; histone cluster 1, H3g; histone cluster 1, H3h; histone cluster 1, H3i; histone cluster 1, H3j; histone cluster 2 H3 family member a; histone cluster 2 H3 family member c; histone cluster 2 H3 family member d; histone cluster 2 H3C family member 2; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone cluster 2, H3d; histone gene complex 1; histone H3; histone H3.1; histone H3/a; histone H3/b; histone H3/c; histone H3/d; histone H3/f; histone H3/h; histone H3/i; histone H3/j; histone H3/k; histone H3/l; histone H3/m; histone H3/o; histone1, H3c; histone1, H3d; unnamed protein product

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基因别名: H3; H3 histone; H3-143; H3-291; H3-53; H3-614; H3-b; H3.1; H3.1-221; H3.2; H3.2-221; H3.2-614; H3.f; H3/A; H3/b; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3c1; H3c10; H3c11; H3c13; H3c14; H3c15; H3c2; H3c3; H3c4; H3c6; H3c7; H3c8; H3F1K; H3F2; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; Hist1; Hist1h2ail; Hist1h2ail1; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; HIST2H3C; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; HIST2H3D