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The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: beta globin chain; Beta-globin; delta globin; Delta-globin; delta-globin chain; Hemoglobin beta chain; Hemoglobin delta chain; Hemoglobin subunit beta; Hemoglobin subunit delta; hemoglobin, beta; hemoglobin, delta
基因别名: beta-globin; CD113t-C; HBB; HBD
UniProt ID: (Human) P68871, (Human) P02042
Entrez Gene ID: (Human) 3043, (Human) 3045