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Proteintech
HBS1L Polyclonal Antibody
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产品信息
10359-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HBS1L Fusion Protein Ag0388 (43-262 aa encoded by BC001465)
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody specifically recognizes the 75 kDa human HBS1L protein.
Immunogen sequence: SRRDKPSVE PVEEYDYEDL KESSNSVSNH QLSGFDQARL YSCLDHMREV LGDAVPDEIL IEAVLKNKFD VQKALSGVLE QDRVQSLKDK NEATVSTGKI AKGKPVDSQT SRSESEIVPK VAKMTVSGKK QTMGFEVPGV SSEENGHSFH TPQKGPPIED AIASSDVLET ASKSANPPHT IQASEEQSST PAPVKKSGKL RQQIDVKAEL EKRQGGKQLL N (43-262 aa encoded by BC001465)
靶标信息
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: eRF3 family member; ERF3-similar protein; ERFS; eukaryotic release factor 3; HBS1-like protein; HBS1-like translational GTPase; Hsp70 subfamily B suppressor 1-like protein
基因别名: 2810035F15Rik; AI326327; EF-1a; eRF3c; ERFS; HBS1; HBS1L; HSPC276; KIAA1038
UniProt ID: (Human) Q9Y450, (Rat) Q6AXM7, (Mouse) Q69ZS7
Entrez Gene ID: (Human) 10767, (Rat) 293408, (Mouse) 56422
