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Antibodies Inc
HCN3 Monoclonal Antibody (N141/28), FL550
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产品信息
75-175-FL550
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N141/28
抗原
Fusion protein amino acids 660-779 (cytoplasmic C-terminus) of mouse HCN3 (accession number O88705) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
550/575 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HAC-3; Hyperpolarization-activated cation channel 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; MGC131493; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
基因别名: BCNG-4; Bcng4; Hac3; Hcn3; Hcn4
UniProt ID: (Mouse) O88705, (Rat) Q9JKA8
Entrez Gene ID: (Mouse) 15168, (Rat) 114245
nucleotide binding
ion channel activity
intracellular cAMP activated cation channel activity
voltage-gated ion channel activity
voltage-gated sodium channel activity
voltage-gated potassium channel activity
potassium channel activity
sodium channel activity
protein binding
cAMP binding
ion channel
transporter
transport
ion transport
potassium ion transport
sodium ion transport
regulation of ion transmembrane transport
sodium ion transmembrane transport
regulation of membrane potential
transmembrane transport
potassium ion transmembrane transport
cellular response to cAMP
response to cisplatin
cellular response to dopamine
