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Invitrogen
HCN4 Polyclonal Antibody
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HCN4 Antibody (PA5-111793) in IHC (F)
Immunohistochemistry analysis of HCN4 in frozen mouse thalamus tissue sections using HCN4 Antibody (Product # PA5-111793). A) Staining of HCN4 (green) appears in the ventral posterior thalamic nucleus (VPL). B) In the same section as in A, staining of HCN2 (red) appears in the ventral posterior thalamic nucleus (VPL) and also in the reticular thalamic nucleus (RT). The area between these thalamic nuclei (st... View More
产品信息
PA5-111793
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Guinea pig
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GST fusion protein corresponding to amino acid residues 119-155 of human HCN4 (Intracellular, N-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
GST fusion protein sequence is: HGHLHDSAEE RRLIAEGDA SPGEDRTPPG LAAEPERP
Homology: Rabbit amino acid residues identical; rat - 35/37 amino acid residues identical; mouse - 33/37 amino acid residues identical.
靶标信息
HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
