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Invitrogen
HDAC2 Polyclonal Antibody
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产品信息
PA1-26832
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, conjugated to KLH, corresponding to residues C-S(471) G E K T D T K G T K S E Q L S N P(488) of human HDAC 2.
偶联物
形式
Liquid
浓度
15 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-26832 detects HDAC2 from human, mouse, and rat samples. PA1-26832 is expected to cross react with chicken (94% conserved) due to sequence homology.
PA1-26832 has been successfully used in immunoprecipitation, ChIP assay and Western blot procedures. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. The predicted molecular weight of PA1-26832 is 55.3 kDa.
The PA1-26832 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues C-S(471) G E K T D T K G T K S E Q L S N P(488) of human HDAC 2.
靶标信息
HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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