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Invitrogen
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PA1-27944 detects HEY1 from human, mouse, rat samples.
PA1-27944 may be successfully used in ELISA and Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27835 immunogen is a synthetic peptide corresponding to human Hairy/enhancer-of-split related with YRPW motif 1.
Store at 4°C short term. For extended storage, aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
Hairy/enhancer-of-split related with YRPW motif protein 1 belongs to the HEY family and is a Notch Signaling Pathway Protein. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. It is a downstream effector of Notch signaling which may be required for cardiovascular development. It acts as transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. It represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Hey1 is also reported to be expressed during development of the nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。