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Invitrogen
HIF3A Polyclonal Antibody
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HIF3A Antibody (PA5-117331) in WB
Western blot analysis of Hif3 alpha in Non-transfected (–) and transfected (+) 293T whole cell extracts (30 µg). Samples were separated with 7.5% SDS-PAGE and incubated in Hif3 alpha polyclonal antibody (Product # PA5-117331) using a dilution of 1:1,000, followed by HRP-conjugated anti-rabbit IgG.
产品信息
PA5-117331
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human HIF3 alpha. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.48 mg/mL
规格
148 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Centrifuge briefly prior to opening.
靶标信息
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (also designated Arnt 1), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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