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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SHLNSCDTNN HNKTSLLRPV ASSSTATLTA NFTKIGTLRS QALTTSAHSV VHHGIPLQAG TAQFGCGDAF QQTLIICPPA IQGIPA
Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 85%.
HIPK3 is a serine/threonine kinase involved in signal transduction, cellular communication, and multidrug resistance of tumors and plays a role in the phosphorylation of FADD. HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: androgen receptor-interacting nuclear protein kinase; ANPK; fas-interacting serine/threonine-protein kinase; FIST; FIST3; protein kinase; homolog of protein kinase YAK1; RP1-8L15.1; unnamed protein product
基因别名: DYRK6; FIST3; PKY; YAK1
UniProt ID: (Human) Q9H422
Entrez Gene ID: (Human) 10114