Invitrogen

HIST1H2AJ Polyclonal Antibody

Name: HIST1H2AJ Polyclonal Antibody
Brand: Invitrogen
SKU: PA5150289

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image HIST1H2AJ Polyclonal Antibody

产品信息

PA5150289

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.5-2 µg/mL

免疫组化（石蜡） (IHC (P))

5-20 µg/mL

免疫细胞化学 (ICC/IF)

5-20 µg/mL

酶联免疫吸附实验 (ELISA)

0.05-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit

分类

Polyclonal

类型

Antibody

抗原

Recombinant Histone Cluster 1, H2aj (HIST1H2AJ) (Met1-Lys128)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

The HIST1H2AJ gene encodes a variant of the H2A family of histones, which are fundamental components of the nucleosome structure in eukaryotic cells. Histones are responsible for packaging DNA into chromatin and play a critical role in regulating gene expression. The modifications of these histones, including those produced by the HIST1H2AJ gene, can influence DNAtemplated processes such as transcription, replication, and repair by altering chromatin structure. The histone modifications are complex and include acetylation, methylation, and lactylation, which serve as a dynamic regulatory mechanism linking cellular metabolism to gene regulation. This connection illustrates the intricate role histone modifications have in responding to cellular stress and damage, thereby impacting processes such as inflammation and cancer development. The comprehensive understanding of histone posttranslational modifications and their effect on gene expression underscores the importance of HIST1H2AJ within the broader study of chromatin dynamics and its influence on human health and disease.

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