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Proteintech
HKR1 Polyclonal Antibody
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产品信息
14902-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HKR1 Fusion Protein Ag6694 (254-599 aa encoded by BC053845)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: NLITHQRTH SGEKPYVCKD CGRGFTWKSN LFTHQRTHSG LKPYVCKECG QSFSLKSNLI THQRAHTGEK PYVCRECGRG FRQHSHLVRH KRTHSGEKPY ICRECEQGFS QKSHLIRHLR THTGEKPYVC TECGRHFSWK SNLKTHQRTH SGVKPYVCLE CGQCFSLKSN LNKHQRSHTG EKPFVCTECG RGFTRKSTLS THQRTHSGEK PFVCAECGRG FNDKSTLISH QRTHSGEKPF MCRECGRRFR QKPNLFRHKR AHSGAFVCRE CGQGFCAKLT LIKHQRAHAG GKPHVCRECG QGFSRQSHLI RHQRTHSGEK PYICRKCGRG FSRKSNLIRH QRTHSG (254-599 aa encoded by BC053845)
靶标信息
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppeltype DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GLI-Kruppel family member HKR1; Krueppel-related zinc finger protein 1; oncogene HKR1; Protein HKR1; Zinc finger protein 875
基因别名: HKR1; ZNF875
UniProt ID: (Human) P10072
Entrez Gene ID: (Human) 284459
