Invitrogen

HLA-B7 Monoclonal Antibody (BB7.1)

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HLA-B7 Monoclonal Antibody (BB7.1)

产品信息

MA5-44010

应用
建议稀释比
已发表文章

流式细胞分析 (Flow)

1-4 µg/mL
-
产品规格

种属反应

Human, Non-human primate

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

BB7.1

抗原

Papain solubilised HLA-A2, B7
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

15mM sodium azide

保存条件

4°C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2912942

产品详细信息

This antibody recognizes an extracellular antigen of HLA-B7 antigen. Although highly specific, it can cross-react with HLA-B42 antigen.

靶标信息

HLA-B7 is one of the polymorphic proteins of human MHC Class I found on all nucleated cells. This surface protein is a heterodimer consisting of the specific transmembrane HLA-B chain paired with Beta-2 microglobulin. Classical MHC Class I molecules play a central role in adaptive immunity by presenting to T cells antigenic peptides derived either from the cell itself (classical presentation) or extracellular antigens (cross-presentation). The ligands of MHC class I include T cell receptor (TCR) and a costimulatory molecule CD8. Hundreds of HLA-B alleles have been described. Typing for these polymorphisms is routinely done for transplantation.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CDABP0067; class I MHC, HLA-B antigen; DAQB-90C11.16; epididymis secretory protein Li 83; FLJ26655; histocompatibility antigen; HLA -B; HLA B-40011; HLA B44; hla b7; HLA class I antigen HLA-B; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, B-47 alpha chain; HLA class I histocompatibility antigen, B-50 alpha chain; HLA class I histocompatibility antigen, B-82 alpha chain; HLA locus; HLA molecule; HLA-B; HLA-B 1502; HLA-B alpha chain; HLA-B alpha chain (B*2706); HLA-B alpha chain (B*5002); HLA-B alpha-chain; HLA-B35; HLA-B35 antigen; HLA-Bw50 antigen; Human leukocyte antigen B; hypothetical protein; lecocyte antigen B; Leukocyte Antigen; leukocyte antigen class I-B; Leukoocyte Antigen; lymphocyte antigen; major histocompatability complex B antigen; MHC 1; MHC antigen; MHC class 1 antigen; MHC class I alpha chain; MHC class I anitgen; MHC class I antigen B*47; MHC class I antigen B*50; MHC class I antigen B*82; MHC class I antigen GN00104; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen SHCHA; MHC class I antigene; MHC class I human leukocyte antigen; MHC class I molecule; MHC class I protein; MHC class II antigen; MHC class l antigen; MHC classI antigen; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B27-HS; MHC HLA-B27d; MHC HLA-B39N; MHC1; truncated class I antigen; truncated MHC class I antigen

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基因别名: AS; B-4901; B-5001; Bw-47; Bw-50; HEL-S-83; HLA-B; HLA-B*45ZJ; HLA-B-3506; HLA-B-3905; HLA-B-5502; HLA-B-5602; HLA-B15; HLA-B39; HLA-B49; HLA-B50; HLA-B55; HLA-B59; HLA-B61; HLA-Cw; HLA-DRB1; HLAB; SPDA1

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UniProt ID: (Human) Q29678

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Entrez Gene ID: (Human) 3106

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