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Invitrogen
HLA-DQ1/DQ3 Monoclonal Antibody (HL-37)
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产品信息
MA1-19143
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig
已发表种属
Human
宿主/亚型
Mouse
/ IgG3
分类
Monoclonal
类型
Antibody
克隆号
HL-37
抗原
Burkitt's lymphoma cell line Raji.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts with extracellular polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Western Blot: non-reducing conditions.
靶标信息
Reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated b chain of DQ1), but does not react with HLA-DQ2.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-D; HLA-DQ; HLADQ; HLADQ1; HLADQ3; lymphocyte antigen; MHC Class 2; MHC class II; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; MHC HLA-D; MHC II HLA
基因别名: CELIAC1; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1
UniProt ID: (Human) Q8WMA3
Entrez Gene ID: (Human) 3119
immunoglobulin production involved in immunoglobulin mediated immune response
humoral immune response mediated by circulating immunoglobulin
immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell costimulation
T cell receptor signaling pathway
interferon-gamma-mediated signaling pathway
