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Proteintech
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Immunogen sequence: SYVSEVEIT PSCIPVVTNM EAFSSEHFNL EIYRQNLQTK QLGKVILFAE VTPTTMRLLD GLMFQTPQEM GLIVIAARQT EGKGRGGNVW LSPVGCALST LLISIPLRSQ LGQRIPFVQH LMSVAVVEAV RSIPEYQDIN LRVKWPNDIY YSDLMKIGGV LVNSTLMGET FYILIGCGFN VTNSNPTICI NDLITEYNKQ HKAELKPLRA DYLIARVVTV LEKLIKEFQD KGPNSVLPLY YRYWVHSGQQ VHLGSAEGPK VSIVGLDDSG FLQVHQEGGE VVTVHPDGNS FDMLRNLILP KRR (425-726 aa encoded by BC060787)
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Biotin apo-protein ligase; biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase; biotin--[acetyl-CoA-carboxylase] ligase; biotin--[methylcrotonoyl-CoA-carboxylase] ligase; biotin--[methylmalonyl-CoA-carboxytransferase] ligase; Biotin--protein ligase; holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
基因别名: 410I21.SP6; D16Jhu34; HCS; HLCS; RGD1565360
UniProt ID: (Human) P50747, (Mouse) Q920N2
Entrez Gene ID: (Human) 3141, (Rat) 288240, (Mouse) 110948