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Proteintech
HMGCL Polyclonal Antibody
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产品信息
16898-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HMGCL Fusion Protein Ag10426 (1-325 aa encoded by BC010570)
偶联物
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAAMRKALP RRLVGLASLR AVSTSSMGTL PKRVKIVEVG PRDGLQNEKN IVSTPVKIKL IDMLSEAGLS VIETTSFVSP KWVPQMGDHT EVLKGIQKFP GINYPVLTPN LKGFEAAVAA GAKEVVIFGA ASELFTKKNI NCSIEESFQR FDAILKAAQS ANISVRGYVS CALGCPYEGK ISPAKVAEVT KKFYSMGCYE ISLGDTIGVG TPGIMKDMLS AVMQEVPLAA LAVHCHDTYG QALANTLMAL QMGVSVVDSS VAGLGGCPYA QGASGNLATE DLVYMLEGLG IHTGVNLQKL LEAGNFICQA LNRKTSSKVA QATCKL (1-325 aa encoded by B C010570)
靶标信息
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxy-3-methylglutaryl-Coenzyme A lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; HL; HMG-CoA lyase; hydroxymethylglutaricaciduria; Hydroxymethylglutaryl-CoA lyase, mitochondrial; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
基因别名: AW476067; HL; HMGCL
UniProt ID: (Human) P35914, (Mouse) P38060, (Rat) P97519
Entrez Gene ID: (Human) 3155, (Mouse) 15356, (Rat) 79238
